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Test Code YMCRO Y Chromosome Microdeletions, Molecular Detection, Varies

Genetics Test Information

Tests for the presence of microdeletions in the AZFa, AZFb, and AZFc regions of the Y chromosome.

Specimen Type

Varies


Shipping Instructions


 



Specimen Required


Patient Preparation: A previous bone marrow transplant from an allogeneic donor will interfere with testing. For instructions for testing patients who have received a bone marrow transplant, call 800-533-1710.

Specimen Type: Whole blood

Container/Tube: 

Preferred: Lavender top (EDTA) or yellow top (ACD)

Acceptable: None

Specimen Volume: 3 mL

Collection Instructions:

1. Invert several times to mix blood.

2. Send whole blood specimen in original tube. Do not aliquot.

Additional Information:

1. Specimens are preferred to be received within 4 days of collection. Extraction will be attempted for specimens received after 4 days, and DNA yield will be evaluated to determine if testing may proceed.

2. To ensure minimum volume and concentration of DNA is met, the preferred volume of blood must be submitted. Testing may be canceled if DNA requirements are inadequate.


Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
  Frozen 
  Refrigerated 

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Day(s) Performed

Wednesday

Report Available

7 to 10 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

81403-DAZ/SRY (deleted in azoospermia and sex determining region Y) (eg, male infertility), common deletions (eg, AZFa, AZFb, AZFc, AZFd)

Specimen Minimum Volume

See Specimen Required

Reference Values

An interpretive report will be provided.

Specimen Retention Time

Whole blood: 2 weeks (if available); Extracted DNA: 3 months