Ordering Guidance

Random urine collections are preferred for patients with episodic symptoms, (eg, in the context of allergic reactions brought on by specific environmental factors or mast cell activation syndrome). For random urine collection, order RLTE4 / Leukotriene E4, Random, Urine.

Additional Testing Requirements

For an optimal evaluation, testing for urinary leukotriene E4 should be accompanied with laboratory investigations for the presence of serum tryptase (TRYPT / Tryptase, Serum), urinary 2,3-dinor 11 beta-prostaglandin F2 alpha (23BPT / 2,3-Dinor 11 Beta-Prostaglandin F2 Alpha, 24 Hour, Urine) and urinary N-methylhistamine (NMH24 / N-Methylhistamine, 24 Hour, Urine).

Necessary Information

Specimen volume (in milliliters) and duration are required.

Specimen Required

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Container/Tube: Plastic vial

Specimen Volume: 5 mL

Collection Instructions:

1. Start collection within a few hours of symptom onset and collect urine for 24 hours

2. No preservative preferred

3. Aliquot urine into a plastic vial and send frozen.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collection.