Test Code THIO Thiopurine Metabolites, Whole Blood
Ordering Guidance
This specimen cannot be shared with any other testing, including tacrolimus, cyclosporine, sirolimus or everolimus. Additional testing must be ordered separately and separate specimen submitted.
Shipping Instructions
Specimen must be shipped refrigerated.
Specimen Required
Container/Tube: Lavender top (EDTA)
Specimen Volume: 3 mL
Collection Instructions: Send whole blood specimen in original tube. Do not aliquot, centrifuge, or freeze.
Specimen Type
Whole Blood EDTASpecimen Minimum Volume
1.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood EDTA | Refrigerated (preferred) | 8 days |
| Ambient | 24 hours |
Reject Due To
| Gross hemolysis | Reject |
| Moderate hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
| Clotted | Reject |
| Specimens that have been aliquoted or centrifuged | Reject |
Reference Values
6-Thioguanine Nucleotides (6-TGN): 235-450 pmol/8x10(8) red blood cell (RBC)
6-Methylmercaptopurine (6-MMP): Less than or equal to 5700 pmol/8x10(8) RBC
Day(s) Performed
Monday, Wednesday, Friday
Report Available
2 to 4 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester