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Test Code RSMPU Monoclonal Protein Screen, Random, Urine


Ordering Guidance


The use of a random urine specimen is sufficient for identifying the presence or absence of monoclonal proteins, but a 24-hour specimen is preferred for quantitating and monitoring the abnormality. See SMPU / Monoclonal Protein Screen, 24 Hour, Urine.



Shipping Instructions


Refrigerate specimen after collection and send refrigerated.



Specimen Required


Supplies: Urine Container, 60 mL (T313)

Submission Container/Tube: Plastic, 60-mL urine bottle

Specimen Volume: 50 mL

Collection Instructions:

1. Collect random urine specimen.

2. Aliquot between 30 mL and 50 mL of urine into a plastic, 60 mL urine bottle.


Reflex Tests

Test ID Reporting Name Available Separately Always Performed
RPEU Protein Electrophoresis, Random, U No No

Specimen Type

Urine

Specimen Minimum Volume

30 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  5 days
  Ambient  24 hours

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

CREATININE:

≥18 years old: 16-326 mg/dL

Reference values have not been established for patients younger than 18 years of age.

 

PROTEIN/CREATININE RATIO:

≥18 years: <0.18 mg/mg creatinine

Reference values have not been established for patients younger than 18 years of age.

 

ELECTROPHORESIS, PROTEIN

The following fractions, if present, will be reported as mg/dL:

-Albumin

-Alpha-1-globulin

-Alpha-2-globulin

-Beta-globulin

-Gamma-globulin

No reference values apply to random urines.

 

MASS-FIX M-PROTEIN ISOTYPE

M-protein Isotype MS:

No monoclonal protein detected

 

Flag M-protein Isotype MS:

Negative

Day(s) Performed

Monday through Friday

Report Available

4 to 6 days

Specimen Retention Time

See Individual Test IDs

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84156

82570

84166 Electrophoresis, protein (if appropriate)

0077U