Test Code PYR Pyruvic Acid, Blood
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
Whole bloodAdditional Testing Requirements
This test does not calculate the lactate:pyruvate ratio. To obtain this information, both this test and LACS1 / Lactate, Plasma must be ordered. The ratio can be calculated from the results obtained from these tests. A separate specimen must be obtained for lactate testing, see LACS1 / Lactate, Plasma.
Specimen Required
Call 800-533-1710 or 507-266-5700 to order special collection tube.
Patient Preparation: Fasting (at least 4 hours)
Supplies: Perchloric Acid-Pyruvate Tube (T012)
Container/Tube: Special collection tube containing 2.5 mL of 6% perchloric acid
Specimen Volume: Exactly 1 mL
Collection Instructions:
1. Special collection tube must be prechilled prior to collection.
2. Draw enough blood directly into syringe to add exactly 1 mL of blood to the prechilled special collection tube.
3. Taking care to not spill any of the preservative, cautiously remove the cap from the tube.
4. Immediately transfer blood, once drawn, to the prechilled, special collection tube, recap, and shake vigorously to mix.
Additional Information:
1. Check expiration date before using. Supplied collection tube expires 14 months after preparation.
2. If perchloric acid (preservative) spills, obtain a new, prechilled tube.
Specimen Minimum Volume
See Specimen Required
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole blood | Refrigerated | 15 days | PYRUVATE |
Reference Values
0.08-0.16 mmol/L
NIH Unit
0.7-1.4 mg/dL
Day(s) Performed
Monday, Wednesday
CPT Code Information
84210
Report Available
2 to 5 daysSpecimen Retention Time
3 weeksReject Due To
Gross hemolysis | OK |
Gross lipemia | OK |
Genetics Test Information
The lactate:pyruvate (L:P) ratio is considered a helpful (not diagnostic) tool in the evaluation of patients with possible disorders of mitochondrial metabolism, especially in patients with neurologic dysfunction and either elevated or normal blood lactate levels. Pyruvic acid levels alone have little clinical utility.