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HelpTest Code PQNRU Porphyrins, Quantitative, Random, Urine
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
UrineOrdering Guidance
This random urine test should be ordered when the specimen will reach Mayo Clinic Laboratories within 72 hours. If transportation will take longer than 72 hours, order both PQNU / Porphyrins, Quantitative, 24 Hour, Urine and ALAUR / Aminolevulinic Acid, Urine and follow collection guidelines.
Shipping Instructions
Ship specimen in amber bottle to protect from light.
Necessary Information
Include a list of medications the patient is currently taking.
Specimen Required
Patient Preparation: Patient must not consume any alcohol for at least 24 hours before specimen collection.
Supplies: Urine Container - Amber, 60 mL (T596)
Container/Tube: Amber, 60-mL urine container
Specimen Volume: 20 to 50 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative necessary but pH must be above 5.0. If pH is below 5.0, specimen will be rejected.
3. Specimens should be protected from light and frozen immediately following collection.
Specimen Minimum Volume
15 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Frozen | 72 hours | LIGHT PROTECTED |
Reference Values
Uroporphyrins, Octacarboxyl:
≤3.1 mcmol/mol creatinine
Heptacarboxylporphyrins:
≤0.9 mcmol/mol creatinine
Hexacarboxylporphyrins:
≤0.3 mcmol/mol creainine
Pentacarboxyporphyrins:
≤1.2 mcmol/mol creatinine
Coproporphyrin, Tetra::
≤25.0 mcmol/mol creatinine
Porphobilinogen:
≤0.2 mmol/mol creatinine
Aminolevulinic Acid
≤ 2.3 mmol/mol creatinine
Day(s) Performed
Monday through Friday
CPT Code Information
84110-Porphobilinogen, quantitative
84120-Porphyrins, quantitation and fractionation
82135- ALA Delta Random Urine
Genetics Test Information
This is the preferred test during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria. The random urine collection for this test allows for the diagnosis to be established and treatment to be initiated quickly. However, this test should only be ordered when the specimen will be received at Mayo Clinic Laboratories within 72 hours of collection. If it will be longer than 72 hours, both PQNU / Porphyrins, Quantitative, 24 Hour, Urine and ALAUR / Aminolevulinic Acid, Urine should be ordered and collection guidelines must be followed.
Testing includes porphobilinogen and aminolevulinic acid, which are useful in the evaluation of the acute porphyrias.
This is the preferred test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda.