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HelpTest Code OPATS Opiate Panel, Free (Unconjugated), Serum
Ordering Guidance
This test should only be ordered by healthcare professionals to monitor patients who have been prescribed any of the following opiates/opiates antagonists: codeine, oxycodone, noroxycodone, oxymorphone, hydrocodone, norhydrocodone, dihydrocodeine, morphine, 6-monoacetylmorphine, hydromorphone, and noroxymorphone.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Type
Serum RedSpecimen Minimum Volume
Serum: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 14 days |
| Frozen | 28 days | |
| Ambient | 24 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Therapeutic range/Metabolite information (as applicable):
6-monoacetylmorphine: Metabolite of heroin
Codeine: 10-100 ng/mL
Morphine: 10-80 ng/mL when used as sole therapy; Minor metabolite of codeine
Hydromorphone: 1.0-30 ng/mL when used as sole therapy; Metabolite of hydrocodone and minor metabolite of morphine
Hydrocodone: 10-100 ng/mL
Dihydrocodeine: 72-150 ng/mL when used as sole therapy; Minor metabolite of hydrocodone
Norhydrocodone: Metabolite of hydrocodone
Oxycodone: 10-100 ng/mL
Noroxycodone: Metabolite of oxycodone
Oxymorphone: 1.0-8.0 ng/mL when used as sole therapy; Metabolite of oxycodone
Noroxymorphone: Metabolite of oxymorphone
Cutoff concentrations:
6-Monoacetylmorphine: 1.0 ng/mL
Codeine: 1.0 ng/mL
Morphine: 1.0 ng/mL
Hydromorphone: 1.0 ng/mL
Hydrocodone: 1.0 ng/mL
Dihydrocodeine: 1.0 ng/mL
Norhydrocodone: 1.0 ng/mL
Oxycodone: 1.0 ng/mL
Noroxycodone: 1.0 ng/mL
Oxymorphone: 1.0 ng/mL
Noroxymorphone: 1.0 ng/mL
Day(s) Performed
Wednesday
Report Available
2 to 9 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
G0480
80361 (if appropriate for select payers)
80365 (if appropriate for select payers)
80356 (if appropriate for select payers)