Test Code MMPP Mitochondrial Metabolites, Plasma
Ordering Guidance
This test is not the recommended initial screening test for evaluating patients with suspected mitochondrial disorders, organic acidurias, and ketone body disorders. For these purposes, the preferred tests for first-tier assessment are OAU / Organic Acids Screen, Random, Urine; AAQP / Amino Acids, Quantitative, Plasma; and ACRN / Acylcarnitines, Quantitative, Plasma.
Analytes from LAPYP / Lactate Pyruvate Panel, Plasma are included in this test. If ordered together, LAPYP may be canceled.
Specimen Required
Collection Container/Tube:
Preferred: Green top (Sodium heparin)
Acceptable: Green top (Lithium heparin)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot plasma into a plastic vial.
Specimen Type
PlasmaSpecimen Minimum Volume
0.1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma | Frozen | 7 days |
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | OK |
Gross icterus | OK |
Reference Values
LACTIC ACID
≤ 4000.0 nmol/mL
2-HYDROXYBUTYRIC ACID
≤ 124.0 nmol/mL
3-HYDROXYBUTYRIC ACID
≤ 700.0 nmol/mL
PYRUVIC ACID
≤ 350.0 nmol/mL
cis-ACONITIC ACID
≤ 9.0 nmol/mL
CITRIC ACID
≤ 250.0 nmol/mL
3-HYDROXYPROPIONIC ACID
≤ 12.4 nmol/mL
3-HYDROXY-2-METHYLBUTYRIC ACID
≤ 2.5 nmol/mL
3-HYDROXYISOVALERIC ACID
≤ 15.4 nmol/mL
SUCCINIC ACID
≤ 10.0 nmol/mL
FUMARIC ACID
≤ 5.0 nmol/mL
3-METHYLGLUTACONIC ACID
≤ 1.6 nmol/mL
MALIC ACID
≤ 20.0 nmol/mL
2-KETOBUTYRIC ACID
≤ 16.0 nmol/mL
2-KETOISOVALERIC ACID
≤ 35.0 nmol/mL
ACETOACETIC ACID
≤ 350.0 nmol/mL
3-METHYL-2-KETOVALERIC ACID
≤ 70.0 nmol/mL
2-KETOISOCAPROIC ACID
≤ 70.0 nmol/mL
2-METHYLCITRIC ACID
≤ 1.0 nmol/mL
2-KETOGLUTARIC ACID
≤ 40.0 nmol/mL
Day(s) Performed
Wednesday
Report Available
3 to 9 daysSpecimen Retention Time
2 monthsPerforming Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
82542