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Test Code LLPT Leukemia/Lymphoma Immunophenotyping, Flow Cytometry, Tissue

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
FCINT Flow Cytometry Interp, 2-8 Markers No, (Bill Only) No
FCIMS Flow Cytometry Interp, 9-15 Markers No, (Bill Only) No
FCINS Flow Cytometry Interp,16 or greater No, (Bill Only) No

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Tissue


Ordering Guidance


Order LCMS / Leukemia/Lymphoma Immunophenotyping, Flow Cytometry, Varies if the specimen is a fresh (less than 4 days post-collection), unfixed, non-embedded bone marrow core biopsy, bone or bone lesion. This is an equivalent source for bone marrow aspirate only in the event of a dry tap during the bone marrow harvesting procedure. Indicate “dry tap" in performing lab notes or paperwork when submitting this specimen type.

 

This test is not intended for product of conception (POC) specimens. For POC specimens see CMAPC / Chromosomal Microarray, Autopsy, Products of Conception, or Stillbirth.



Shipping Instructions


Specimen must arrive within 4 days of collection.



Necessary Information


The following information is required:

1. Pertinent clinical history, including reason for testing or clinical indication/morphologic suspicion

2. Provide the following:

-Tissue type

-Location

-Pathology/diagnostic report, including the client surgical pathology case number



Specimen Required


Submit 1 of the following specimens:

 

Preferred

Specimen Type: Tissue

Supplies: Hank's Solution (T132)

Container/Tube: Sterile container with 15 mL of tissue culture medium (eg, Hank's balanced salt solution, RPMI, or equivalent)

Specimen Volume: 5 mm(3) or larger biopsy

Collection Instructions:

1. Place tissue into a sterile container with 15 mL of tissue culture medium (eg, Hank's balanced salt solution, RPMI, or equivalent).

2. Send intact specimen (do not mince)

3. Specimen cannot be fixed.

Specimen Stability Information: Ambient 4 days/Refrigerated 4 days

 

Acceptable

Specimen Type: Fine needle aspirate (FNA)

Supplies: Hank's Solution (T132)

Container/Tube: Sterile container with 15 mL of tissue culture medium (eg, Hank's balanced salt solution, RPMI, or equivalent)

Specimen Volume: Entire collection

Collection Instructions:

1. Collect FNA and transfer entire collection into a sterile container with 15 mL of tissue culture medium (eg, Hank's balanced salt solution, RPMI, or equivalent).

2. Send intact specimen (do not mince)

3. Specimen cannot be fixed.

Specimen Stability Information: Ambient 4 days/Refrigerated 4 days


Specimen Minimum Volume

1 mm(3)

Specimen Stability Information

Specimen Type Temperature Time
Tissue Refrigerated (preferred)
  Ambient 

Reference Values

An interpretive report will be provided.

Day(s) Performed

Monday through Saturday

Report Available

1 to 4 days

Reject Due To

Fixed, paraffin-embedded, or minced
tissue
Reject
Dry tissue without transport
medium
Reject

CPT Code Information

88184-Flow cytometry; first cell surface, cytoplasmic or nuclear marker x 1

88185-Flow cytometry; additional cell surface, cytoplasmic or nuclear marker (each)

88187-Flow Cytometry Interpretation, 2 to 8 Markers (if appropriate)

88188-Flow Cytometry Interpretation, 9 to 15 Markers (if appropriate)

88189-Flow Cytometry Interpretation, 16 or More Markers (if appropriate)

Specimen Retention Time

Remaining tissue 7 days