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Test Code LBCS Labile Bound Copper, Serum


Ordering Guidance


If CUS1 / Copper, Serum is ordered with this test, it will be canceled, as copper testing will be automatically added as a part of this test order.



Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for at least 96 hours.

Supplies:

-Metal Free Specimen Vial (T173)

-Metal Free B-D Tube (No Additive), 6 mL (T184)

Collection Container/Tube: 6-mL Plain, royal blue-top Vacutainer plastic trace element blood collection tube

Submission Container/Tube: 7-mL Metal-free, screw-capped, polypropylene vial

Specimen Volume: 0.75 mL

Collection Instructions:

1. For complete instructions, see Metals Analysis Specimen Collection and Transport.

2. Allow the specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction.

3. Remove the stopper. Carefully pour specimen into metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.

4. Freeze sample on dry ice immediately after pouring off the serum.


Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen 28 days METAL FREE

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus Reject

Reference Values

Labile Bound Copper: <105 ng/mL

 

Labile Bound Copper Fraction:

Males: <10.5 %

Females: <8.1 %

 

Copper, Total:

0-2 months: 40-140 mcg/dL

3-6 months: 40-160 mcg/dL

7-9 months: 40-170 mcg/dL

10-12 months: 80-170 mcg/dL

13 months-10 years: 80-180 mcg/dL

11-17 years: 75-145 mcg/dL

Males:

≥18 years: 73-129 mcg/dL

Females:

≥18 years: 77-206 mcg/dL

Day(s) Performed

Wednesday

Report Available

7 to 14 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82525