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Test Code IHC Mismatch Repair (MMR) Protein Immunohistochemistry Only, Tumor

Specimen Type

Varies


Necessary Information


Pathology report (final or preliminary) at minimum containing the following information must accompany specimen for testing to be performed:

1. Patient name

2. Block number-must be on all blocks, slides, and paperwork (can be handwritten on the paperwork)

3. Tissue collection date

4. Source of the tissue



Specimen Required


Tumor tissue is required.

 

Preferred:

Specimen Type: Tissue block

Collection Instructions: Submit formalin-fixed, paraffin-embedded tissue block.

 

Acceptable:

Specimen Type: Tissue slide

Slides: 1 Hematoxylin and eosin stained and 10 unstained

Collection Instructions: Submit 1 slide stained with hematoxylin and eosin and 10 unstained, nonbaked slides (5-micron-thick sections) of tumor tissue.


Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
  Refrigerated 

Reject Due To

Specimens that have been decalcified (all methods)
Specimens that have not been formalin-fixed, paraffin-embedded
Bone marrow in EDTA
Reject

Reference Values

An interpretive report will be provided.

Day(s) Performed

Varies

Report Available

5 to 8 days

Specimen Retention Time

FFPE tissue: Unused portions of FPPE blocks will be returned. Unused, unstained slides: 5 years; Stained slides: Indefinitely.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

88341 MLH1, MLH2, or MLH6 (if appropriate)

88342 PMS2 (if appropriate)