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HelpTest Code FENTS Fentanyl, Serum
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 2.3 mL
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
1.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Frozen (preferred) | 28 days |
| Refrigerated | 14 days | |
| Ambient | 72 hours |
Reference Values
Fentanyl:
Average serum fentanyl concentrations 24 hours after application of transdermal patch:
25 mcg/hour: 0.3-1.2 ng/mL
50 mcg/hour: 0.6-1.8 ng/mL
75 mcg/hour: 1.1-2.6 ng/mL
100 mcg/hour: 1.9-3.8 ng/mL
(Baselt RC. Disposition of Toxic Drugs and Chemical in Man. 12th ed. Biomedical Publications; 2020)
Norfentanyl:
Reference range: Not established
Cutoff concentrations by liquid chromatography tandem mass spectrometry:
Fentanyl: 0.05 ng/mL
Norfentanyl: 0.25 ng/mL
Day(s) Performed
Tuesday, Thursday
CPT Code Information
G0480
80354 (if appropriate for select payers)
Report Available
2 to 7 daysSpecimen Retention Time
14 daysReject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |