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Test Code DMNES Peripheral Nervous System Demyelinating Neuropathy, Autoimmune Evaluation, Serum


Ordering Guidance


Multiple neurological phenotype-specific autoimmune/paraneoplastic evaluations are available. For more information as well as phenotype-specific testing options, refer to Autoimmune Neurology Test Ordering Guide.

 

For a list of antibodies performed with each evaluation, see Autoimmune Neurology Antibody Matrix.



Specimen Required


Patient Preparation: For optimal antibody detection, specimen collection is recommended to occur prior to initiation of immunosuppressant medication or intravenous immunoglobulin treatment.

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Reflex Tests

Test ID Reporting Name Available Separately Always Performed
IGDTS IgG Disialo GD1b Titer, S No No
IMDTS IgM Disialo GD1b Titer, S No No
IGMTS IgG Monos GM1 Titer, S No No
IMMTS IgM Monos GM1 Titer, S No No

Specimen Type

Serum

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

Contactin-1 IgG CBA: Negative

GQ1b-IgG ELISA: Negative

IgG Disialo. GD1b: Negative

IgM Disialo. GD1b: Negative

IgG Monos. GM1: Negative

IgM Monos. GM1: Negative

MAG IgM: <1500 Buhlmann titer unit

Neurofascin-155 IgG4: Negative

 

Reflex Information:

IgG Disialo GD1b Titer: <1:2000

IgM Disialo GD1b Titer: <1:2000

IgG Monos GD1b Titer: <1:2000

IgM Monos GD1b Titer: <1:4000

Day(s) Performed

Monday through Sunday

Report Available

5 to 8 days

Specimen Retention Time

28 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83516 x5

83520

86255 x2

83520 x4 (if applicable)