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Test Code CREA Creatinine with Estimated GFR (CKD-EPI 2021), Plasma or Serum

Additional Codes

LAB66

Collection Method

Venous collection

Minimum Volume

0.5ml

Container

Lt Green / Plasma Separator / Lithium Heparin

Acceptable Specimens

Serum:

  • Gold Top SST
  • Red Top


Plasma:

  • Light Geen Top (lithium heparin)

Reference or Target Ranges

Creatinine

Age Male Female

0 days up to 7 days

 0.2-1.1 0.2-1.1
7 days up to 2 months 0.1-0.6 0.1-0.6

2 months up to 2 years

 0.1-0.5 0.1-0.5
2 years up to 10 years 0.1-0.7 0.1-0.6
10 years up to 14 years 0.3-0.9 0.2-0.8
>14 years 0.7-1.30 0.5-1.10

 

EGFR- ≥60 mL/min/1.73m2

 

The formula for the 2021 CKD-EPI creatinine equation is:

  • eGFR = 142 × min(SCr/κ,1)α × max(SCr/κ,1)-1.200 × 0.9938Age × 1.012 [if female] 

This equation uses standardized serum creatinine (SCr), a kappa value (κ) based on sex (0.7 for females, 0.9 for males), an alpha value (α) based on sex (-0.241 for females, -0.302 for males), and age in years. "min" and "max" in the formula indicate the minimum and maximum of SCr/κ or 1, respectively. 

  • eGFR not calculated for age < 18 years
  • Clinical practice guidelines suggest the use of serum cystatin C as a confirmatory test for eGFR 45-59 ml/min/1.73m2 in adults who do not have markers of kidney disease; eGFR may be less accurate in this range.

Reportable Units

mg/dL

Critical Value

Not defined for this assay

Reasons for Rejection

Hemolysis Threshold 800 mg/dL
Icterus Threshold

5 mg/dL conjugated

10 mg/dL unconjugated
Lipemia Threshold 1000 mg/dL
Other QNS, contaminated, improperly Labeled, improper specimen type

Specimen Stability

Ambient 7 days
Refrigerated (4°C to 8°C) 7 days
Frozen(-40°C to 0°C) 3 months

Performance Information

Days and Time Performed 24/7
Expected Turn Around Time Stat: 1 hour
Routine: 4 hours
Stat Availability Yes
Performing Bench CPH Chemistry
Methodology/Method Description Roche Cobas

CPT Codes

82565

Last review/edit date

2025