Test Code BIOTS Biotinidase, Serum
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumOrdering Guidance
Molecular testing is available, see BTD / Biotinidase Deficiency, BTD Gene Sequencing with Deletion/Duplication, Varies.
If measurement of biotin concentration is requested, order BIOTN / Biotin, Serum.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
Serum: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen (preferred) | 21 days |
| Refrigerated | 5 days |
Reference Values
3.5-13.8 U/L
Day(s) Performed
Monday, Thursday
CPT Code Information
82261
Genetics Test Information
Preferred test to rule out biotinidase deficiency.
Report Available
2 to 5 daysSpecimen Retention Time
30 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |