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Mayo Clinic Laboratories

Test Code B12 Vitamin B12, Serum

Additional Codes

LAB67

Patient Preparation

Fasting recommended

Special Collection Instructions

Samples should not be taken from patients receiving therapy with high biotin doses (i.e. >5 mg/day) until at least 8 hours following the last biotin administration.

Collection Method

Venous collection

Minimum Volume

0.5ml

Container

Serum (SST or red top tube)

Acceptable Specimens

Serum:

  • Gold Top SST
  • Red Top

Plasma:

  • Light Geen Top (lithium heparin)

Reference or Target Ranges

Age Male Female
All ages 211-946 211-946

 

Reportable Units

pg/mL

Critical Value

Not defined for this assay

Reasons for Rejection

Hemolysis Threshold 400 mg/dL
Icterus Threshold 65 mg/dL
Lipemia Threshold 1500 mg/dL
Other QNS, contaminated, improperly Labeled, improper specimen type

Specimen Stability

Ambient Not listed, refrigerate ASAP
Refrigerated (4°C to 8°C) Serum SST: 24 hours
All other tubes: 48 hours
Frozen(-40°C to 0°C) 2 weeks

Performance Information

Days and Time Performed 24/7
Expected Turn Around Time

Stat: 1 hour

Routine: 4 hours

Stat Availability Yes
Performing Bench CPH Chemistry
Methodology/Method Description Roche Cobas 

CPT Codes

82607

Last review/edit date

2025