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Test Code ALDNA Aldosterone with Sodium, 24 Hour, Urine

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Necessary Information


24-Hour volume (in milliliters) is required.



Specimen Required


Patient Preparation: Spironolactone (Aldactone) should be discontinued for 4 to 6 weeks before testing. The plasma renin activity cannot be interpreted if the patient is being treated with spironolactone.

Supplies: Sarstedt Aliquot Tube 5mL (T914)

Container/Tube: 2 Plastic, 5-mL tubes

Specimen Volume: 10 mL

Collection Instructions:

1. Add 25 mL of 50% acetic acid as preservative at start of collection. Use 15 mL of 50% acetic acid for children under the age of 5 years. This preservative is intended to achieve a pH of between approximately 2 and 4.

2. Collect urine for a full 24 hours (required) and record the total volume.

3. Place 5 mL of well mixed, 24-hour urine in plastic, 5-mL tube and label as Aldosterone.

4. Place 5 mL of well mixed, 24-hour urine in plastic, 5-mL tube and label as Sodium.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  7 days

Reference Values

ALDOSTERONE

0-30 days: 0.7-11.0 mcg/24 h*

1-11 months: 0.7-22.0 mcg/24 h*

≥1 year: 2.0-20.0 mcg/24 h

 

*Loeuille GA, Racadot A, Vasseur P, Vandewalle B. Blood and urinary aldosterone levels in normal neonates, infants and children. Pediatrie 1981;36(5):335-344

 

SODIUM

41-227 mmol/24 h

If the 24-hour urinary sodium excretion is greater than 200 mmol, the urinary aldosterone excretion should be less than10 mcg.

Day(s) Performed

Tuesday, Thursday

CPT Code Information

82088-Aldosterone

84300-Sodium

Report Available

2 to 8 days

Specimen Retention Time

See Individual Unit Codes

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Urine Preservative Collection Options

Note: The addition of preservative must occur prior to beginning the collection.

Ambient (no additive)

No

Refrigerate (no additive)

No

Frozen (no additive)

No

50% Acetic Acid

Preferred

Boric Acid

OK

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

No

Toluene

No