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HelpTest Code WBGDD Beta-Globin Gene Cluster, Deletion/Duplication, Varies
Additional Testing Requirements
Hemoglobin electrophoresis studies performed at Mayo Clinic Laboratories are highly recommended prior to this test to allow for more complete interpretation of results. See HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood or THEV1 / Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum.
Shipping Instructions
Specimens must arrive within 4 days (96 hours) of collection.
Necessary Information
Metabolic Hematology Patient Information (T810) is required. Send a completed form with the specimen. Document the reason for suspecting a large beta cluster locus deletion along with the hemoglobin F percentage and red blood cell indices for the patient.
Specimen Required
Specimen Type: Whole blood
Container/Tube:
Preferred: Lavender top (EDTA)
Acceptable: Yellow top (ACD)
Specimen Volume: 4 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send specimen in the original tube. Do not aliquot.
Specimen Stability Information: Refrigerated (preferred)/Ambient
Genetics Test Information
This test can be used to identify a variety of conditions (see Highlights) that involve large deletions of the beta-globin gene cluster. These alterations will not be detected by DNA sequencing of the beta-globin gene.
Specimen Type
VariesSpecimen Minimum Volume
2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Varies | Varies | |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Day(s) Performed
Wednesday, Friday
Report Available
25 to 30 daysSpecimen Retention Time
Whole blood: 2 weeks; DNA: 3 monthsPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
81363-HBB (hemoglobin, beta, beta-globin) (e.g. beta thalassemia), duplication/deletion analysis
Reference Values
An interpretive report will be provided